Gastritis vs. Ulcer: Stomach Inflammation vs. Open Sore
Gastritis is inflammation of the stomach lining without tissue loss. A peptic ulcer is a deeper erosion that breaks through the mucosal layer. Both are often caused by H. pylori infection or NSAID use, but ulcers carry a risk of serious complications like bleeding and perforation.
Key Differences at a Glance
Shared Symptoms
- Upper abdominal pain
- Nausea
- Bloating
- Loss of appetite
Unique Indicators
- Diffuse upper stomach discomfort
- Feeling full quickly
- Night-time pain that wakes from sleep
- Pain relieved (then returned) by eating
- Vomiting blood or coffee-ground material
- Black tarry stools
Professional Diagnosis
Both may require upper endoscopy for definitive diagnosis. H. pylori testing (breath test, stool antigen, or biopsy) is important for both conditions.
Treatment for Gastritis
Proton pump inhibitors to reduce acid, H. pylori eradication if positive, avoiding NSAIDs and alcohol, and dietary modifications.
Treatment for Peptic Ulcer
PPI therapy for 4-8 weeks, H. pylori eradication (triple or quadruple therapy), stopping NSAIDs, and endoscopic intervention for bleeding ulcers.
When to See a Doctor
Seek immediate care for vomiting blood, black tarry stools, sudden severe abdominal pain (possible perforation), or fainting. See a doctor for persistent stomach pain lasting more than 2 weeks.
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Medically Reviewed for Accuracy
Content is aligned with established clinical guidelines from authoritative medical institutions, including MedlinePlus (U.S. National Library of Medicine), the CDC, the NIH, and the NHS. All content is reviewed by our medical advisory board for accuracy and safety.