Bipolar Disorder

Body System: Mental Health & Behavioral System | Area Affected: Brain neurochemistry, mood regulation, and cognitive processes

Doctor to Consult: Psychiatrist or Psychologist

What It Is

Bipolar Disorder: Bipolar disorder (BD), previously known as manic depression, is a mental disorder characterized by periods of depression and abnormally elevated mood, lasting days to weeks, and in some cases months. If the elevated mood is severe or associated with psychosis, it is called mania; if it does not significantly affect functioning, it is called hypomania. During mania, an individual behaves or feels abnormally energetic, happy, or irritable, and often makes impulsive decisions with little regard for the consequences. There is usually sleep disturbance during manic phases. During periods of depression, the individual may experience crying, have a negative outlook, and demonstrate poor eye contact. People with BD are at 11.7 times greater risk of dying by suicide than the general population. Approximately 34% attempt suicide during their lifetime. Among adolescents with BD, 78% engaged in self-harm.

Why It Happens

Bipolar Disorder arises due to factors affecting the Mental Health & Behavioral System. Mental health conditions involve complex interactions between brain chemistry, neural circuitry, psychological experiences, and social environment. While individual cases vary, a combination of genetic susceptibility, lifestyle factors, and environmental exposures typically contribute to the development of Bipolar Disorder.

Who Gets It / Risk Factors

Who Is at Risk for Bipolar Disorder

Can affect anyone at any age, though many conditions first manifest in adolescence or early adulthood.
A family history of mental health & behavioral system conditions may increase susceptibility to Bipolar Disorder.

Contributing Factors

Childhood trauma, chronic stress, social isolation, substance use, and neurobiological vulnerabilities.
Co-existing health conditions such as substance use disorders, chronic pain, or other psychiatric conditions may compound the risk.

When to Seek Emergency Care

Suicidal ideation, self-harm behavior, psychotic episodes, or severe panic attacks associated with Bipolar Disorder.
Sudden or rapidly worsening symptoms that impair basic daily function.
Difficulty breathing, severe pain, loss of consciousness, or high fever with confusion.

Medical Overview

A professional summary of diagnosis, treatment, and prevention.

Persistent changes in mood, energy, sleep, or concentration that may characterize Bipolar Disorder.
Behavioral changes, withdrawal from social activities, or difficulty managing daily responsibilities linked to Bipolar Disorder.
Changes in daily functioning or comfort levels that persist beyond a few days.

Scientific References

This content is based on established clinical guidelines and public health resources from the following authoritative sources.

Medically Reviewed for Accuracy

Medical Advisory Board
Last reviewed: March 20, 2026

Content is aligned with established clinical guidelines from authoritative medical institutions, including MedlinePlus (U.S. National Library of Medicine), the CDC, the NIH, and the NHS. All content is reviewed by our medical advisory board for accuracy and safety.

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