Nausea and Diarrhea: Stomach Bug, Food Poisoning, or Something Else?

Overview

This pairing almost always indicates a gastrointestinal infection (viral gastroenteritis or food poisoning). The digestive tract responds to pathogens by trying to expel them from both ends. Most cases resolve within 1-3 days.

Possible Causes

Viral Gastroenteritis

common

Norovirus or rotavirus infecting the GI tract is the most common cause worldwide.

Food Poisoning

common

Bacterial toxins (Salmonella, E. coli, Staph) cause rapid-onset nausea and diarrhea, usually within 6-24 hours of contaminated food.

IBS Flare

less-common

Stress or dietary triggers can cause simultaneous nausea and diarrhea in IBS patients.

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Medication Side Effect

less-common

Antibiotics, metformin, and NSAIDs commonly cause nausea and diarrhea.

When It Is Serious

Seek care for bloody diarrhea, inability to keep any fluids down for 24+ hours, high fever (>102°F), severe abdominal cramping, or signs of dehydration (no urination, dry mouth).

When It's Likely Benign

Mild cases following a questionable meal that resolve within 48 hours with hydration are typically self-limiting.

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Medically Reviewed for Accuracy

Medical Advisory Board
Last reviewed: March 20, 2026

Content is aligned with established clinical guidelines from authoritative medical institutions, including MedlinePlus (U.S. National Library of Medicine), the CDC, the NIH, and the NHS. All content is reviewed by our medical advisory board for accuracy and safety.